[HTML][HTML] Integration of cellular bioenergetics with mitochondrial quality control and autophagy

BG Hill, GA Benavides, JR Lancaster Jr… - Biological …, 2012 - degruyter.com
Bioenergetic dysfunction is emerging as a cornerstone for establishing a framework for
understanding the pathophysiology of cardiovascular disease, diabetes, cancer and …

The Bioenergetic Health Index: a new concept in mitochondrial translational research

BK Chacko, PA Kramer, S Ravi, GA Benavides… - Clinical …, 2014 - portlandpress.com
Bioenergetics has become central to our understanding of pathological mechanisms, the
development of new therapeutic strategies and as a biomarker for disease progression in …

Hydrogen sulfide mediates the vasoactivity of garlic

GA Benavides, GL Squadrito… - Proceedings of the …, 2007 - National Acad Sciences
The consumption of garlic is inversely correlated with the progression of cardiovascular
disease, although the responsible mechanisms remain unclear. Here we show that human …

Assessing bioenergetic function in response to oxidative stress by metabolic profiling

BP Dranka, GA Benavides, AR Diers… - Free Radical Biology …, 2011 - Elsevier
It is now clear that mitochondria are an important target for oxidative stress in a broad range
of pathologies, including cardiovascular disease, diabetes, neurodegeneration, and cancer. …

Polarographic measurement of hydrogen sulfide production and consumption by mammalian tissues

JE Doeller, TS Isbell, G Benavides, J Koenitzer… - Analytical …, 2005 - Elsevier
The role of nitric oxide (NO) in redox cell signaling is widely accepted. However, the biological
role of another candidate small inorganic signaling molecule and the subject of this study, …

Direct NaBH4/H2O2 fuel cells

…, E Byrd, R Gimlin, PJ Shrestha, G Benavides… - Journal of Power …, 2007 - Elsevier
A fuel cell (FC) using liquid fuel and oxidizer is under investigation. H 2 O 2 is used in this FC
directly at the cathode. Either of two types of reactant, namely a gas-phase hydrogen or an …

[HTML][HTML] Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons

M Redmann, GA Benavides, TF Berryhill, WY Wani… - Redox biology, 2017 - Elsevier
Autophagy is an important cell recycling program responsible for the clearance of damaged
or long-lived proteins and organelles. Pharmacological modulators of this pathway have …

[HTML][HTML] Mitochondrially targeted compounds and their impact on cellular bioenergetics

C Reily, T Mitchell, BK Chacko, GA Benavides… - Redox biology, 2013 - Elsevier
… Chacko, and Gloria Benavides performed seahorse experiments and data analysis; Michael
P. Murphy, Tanecia Mitchell, Colin Reily, and Victor Darley-Usmar wrote the manuscript and …

Differentiation of SH-SY5Y cells to a neuronal phenotype changes cellular bioenergetics and the response to oxidative stress

…, BR Zelickson, MS Johnson, GA Benavides… - Free Radical Biology …, 2011 - Elsevier
Cell differentiation is associated with changes in metabolism and function. Understanding
these changes during differentiation is important in the context of stem cell research, cancer, …

A novel approach to measure mitochondrial respiration in frozen biological samples

…, A Petcherski, M Veliova, GA Benavides… - The EMBO …, 2020 - embopress.org
Respirometry is the gold standard measurement of mitochondrial oxidative function, as it
reflects the activity of the electron transport chain complexes working together. However, the …