Neuropeptides that are released from dendrites, such as oxytocin and vasopressin, function
as autocrine or paracrine signals at their site of origin, but can also act at distant brain …

… To calculate the M/P ratio, the maximal mid-expiratory flow on a P and complete M expiratory
flow volume curve are compared. An M/P ratio of 1 indicates that the deep inspiration …

Despite widespread reports that intranasal application of oxytocin has a variety of
behavioral effects, very little of the huge amounts applied intranasally appears to reach the …

Pancreatic cancer is one of the most lethal malignancies due to its late diagnosis and limited
response to treatment. Tractable methods to identify and interrogate pathways involved in …

Mass spectrometry is a predominant experimental technique in metabolomics and related
fields, but metabolite structural elucidation remains highly challenging. We report SIRIUS 4 ( …

Molecular networking has become a key method to visualize and annotate the chemical space
in non-targeted mass spectrometry data. We present feature-based molecular networking …

Eosinophil-derived TGF-β has been implicated in remodeling events in asthma. We hypothesized
that reduction of bronchial mucosal eosinophils with anti–IL-5 would reduce markers …

Blood pH is maintained in a narrow range around pH 7.4 mainly through regulation of respiration
and renal acid extrusion 1 , 2 . The molecular mechanisms involved in pH homeostasis …

Metabolomics using nontargeted tandem mass spectrometry can detect thousands of molecules
in a biological sample. However, structural molecule annotation is limited to structures …

The crystal structure of a 27-kilodalton methylcobalamin-containing fragment of methionine
synthase from Escherichia coli was determined at 3.0 Å resolution. This structure depicts …