Cannabis use has been reported to induce long-lasting psychotic disorders and a dose-response
relationship has been observed. We performed a systematic review of studies that …

Genome-wide association studies have shown unequivocally that common complex disorders
have a polygenic genetic architecture and have enabled researchers to identify genetic …

The association between urbanicity and risk of schizophrenia is well established. The incidence
of schizophrenia has been observed to increase in line with rising levels of urbanicity, …

… was 9.58 at a location 5 cM proximal to D13S260. However, … two markers is estimated to be
6 cM (7), and these flanking … in an interval of approximately 6 cM, or closer flanking markers…

A genome-wide association scan in individuals with Crohn's disease by the Wellcome Trust
Case Control Consortium detected strong association at four novel loci. We tested 37 SNPs …

Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown.
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …

Major depression is a debilitating psychiatric illness that is typically associated with low
mood and anhedonia. Depression has a heritable component that has remained difficult to …

… Each marker for each scan was assigned to 1 of 120 30-cM bins, with the bins ranked by
linkage scores (1 = most significant) and the ranks averaged across studies (R avg ) and then …

A polygenic risk score (PRS) is a sum of trait-associated alleles across many genetic loci,
typically weighted by effect sizes estimated from a genome-wide association study. The …

Background Cannabis use is associated with increased risk of later psychotic disorder but
whether it affects incidence of the disorder remains unclear. We aimed to identify patterns of …