[PDF][PDF] The PI3K pathway in human disease
DA Fruman, H Chiu, BD Hopkins, S Bagrodia… - Cell, 2017 - cell.com
Phosphoinositide 3-kinase (PI3K) activity is stimulated by diverse oncogenes and growth
factor receptors, and elevated PI3K signaling is considered a hallmark of cancer. Many PI3K …
factor receptors, and elevated PI3K signaling is considered a hallmark of cancer. Many PI3K …
Dementia with Lewy bodies
…, J Mintzer, D Aarsland, D Burn, H Chiu… - The Lancet …, 2004 - thelancet.com
Dementia with Lewy bodies (DLB) is the second commonest cause of neurodegenerative
dementia in older people. It is part of the range of clinical presentations that share a neuritic …
dementia in older people. It is part of the range of clinical presentations that share a neuritic …
Diagnostic accuracy of the Berlin questionnaire, STOP-BANG, STOP, and Epworth sleepiness scale in detecting obstructive sleep apnea: A bivariate meta-analysis
Obstructive sleep apnea (OSA) is a highly prevalent sleep disorder; however, it remains
underdiagnosed and undertreated. Although screening tools such as the Berlin questionnaire (…
underdiagnosed and undertreated. Although screening tools such as the Berlin questionnaire (…
100-GHz transistors from wafer-scale epitaxial graphene
… The cutoff frequency f T is the frequency at which the current gain |h 21 | becomes unity and
signifies the highest frequency at which signals are propagated. For a gate length of 240 nm, …
signifies the highest frequency at which signals are propagated. For a gate length of 240 nm, …
Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
The human kidney contains up to 2 million epithelial nephrons responsible for blood filtration.
Regenerating the kidney requires the induction of the more than 20 distinct cell types …
Regenerating the kidney requires the induction of the more than 20 distinct cell types …
Blu-Ice and the Distributed Control System: software for data acquisition and instrument control at macromolecular crystallography beamlines
TM McPhillips, SE McPhillips, HJ Chiu… - Journal of synchrotron …, 2002 - scripts.iucr.org
The Blu-Ice and Distributed Control System (DCS) software packages were developed to
provide unified control over the disparate hardware resources available at a macromolecular …
provide unified control over the disparate hardware resources available at a macromolecular …
[PDF][PDF] The immunoreceptor TIGIT regulates antitumor and antiviral CD8+ T cell effector function
…, X Yu, M Huseni, Y Yang, S Park, V Javinal, H Chiu… - Cancer cell, 2014 - cell.com
Tumors constitute highly suppressive microenvironments in which infiltrating T cells are "exhausted"
by inhibitory receptors such as PD-1. Here we identify TIGIT as a coinhibitory …
by inhibitory receptors such as PD-1. Here we identify TIGIT as a coinhibitory …
Agility index in the supply chain
CT Lin, H Chiu, PY Chu - International Journal of production economics, 2006 - Elsevier
To achieve a competitive edge in the rapidly changing business environment, companies
must align with suppliers and customers to streamline operations, as well as working together …
must align with suppliers and customers to streamline operations, as well as working together …
[HTML][HTML] A novel mouse model of lipotoxic cardiomyopathy
Inherited and acquired cardiomyopathies are associated with marked intracellular lipid
accumulation in the heart. To test the hypothesis that mismatch between myocardial fatty acid …
accumulation in the heart. To test the hypothesis that mismatch between myocardial fatty acid …
Severe acute respiratory syndrome (SARS) in Hong Kong in 2003: stress and psychological impact among frontline healthcare workers
…, EPF Pang, LCW Lam, HFK Chiu - Psychological medicine, 2004 - cambridge.org
Background. The outbreak of severe acute respiratory syndrome (SARS) posed an
unprecedented threat and a great challenge to health professionals in Hong Kong. The study …
unprecedented threat and a great challenge to health professionals in Hong Kong. The study …