Dermal exposure data for mycotoxins are very scarce and fragmentary, despite their widespread
skin contact and hazard toxicity. In this study, the transdermal kinetics of aflatoxin B1 (…

ETHNOPHARMACOLOGICAL RELEVANCE: Plants are often used for skin diseases in
different ethnopharmacological systems. Local and systemic effects of topically applied …

Several sensitive methods have been developed for patulin determination; however, mass
spectrometric (MS) detection of this toxin in the positive electrospray ionization (ESI + ) mode …

Peptides are an increasingly important group of pharmaceuticals, positioned between classic
small organic molecules and larger bio-molecules such as proteins. Currently, the peptide …

Background: Plant N-alkylamides (NAAs) are bio-active compounds with a broad functional
spectrum. In order to reach their pharmacodynamic targets, they have to overcome several …

… testosterone supplementation can be found in the review by De Spiegeleer et al. [38]. …
Anton De Spiegeleer, David Beckwée, Ivan Bautmans and Mirko Petrovic have no conflicts of …

The expression of certain bacterial genes is regulated in a cell-density dependent way, a
phenomenon called quorum sensing. Both Gram-negative and Gram-positive bacteria use this …

Background N-alkylamides (NAAs) are a large group of secondary metabolites occurring in
more than 25 plant families which are often used in traditional medicine. A prominent active …

Cell-penetrating peptides (CPPs) are a group of peptides, which have the ability to cross
cell membrane bilayers. CPPs themselves can exert biological activity and can be formed …

Currently, next to the major classes, cyclic depsipeptides beauvericin and enniatins are also
positioned as mycotoxins. However, as there are hundreds more fungal cyclic …