User profiles for R. Tompkins

Ronald Tompkins

Massachusetts General Hospital/Harvard Medical School
Verified email at mgh.harvard.edu
Cited by 56380

Mesenchymal stem cells: mechanisms of immunomodulation and homing

…, B Parekkadan, Y Kitagawa, RG Tompkins… - Cell …, 2010 - journals.sagepub.com
Mesenchymal stem cell (MSC) transplantation has been explored as a new clinical approach
to repair injured tissue. A growing corpus of studies have highlighted two important aspects …

Support of the metabolic response to burn injury

DN Herndon, RG Tompkins - The Lancet, 2004 - thelancet.com
Severe burn causes metabolic disturbances that can last for a year after injury; persistent
and profound catabolism hampers rehabilitative efforts and delays the meaningful return of …

Plants and animals share functionally common bacterial virulence factors

…, CL Walendziewicz, RG Tompkins - Proceedings of the …, 2000 - National Acad Sciences
By exploiting the ability of Pseudomonas aeruginosa to infect a variety of vertebrate and
nonvertebrate hosts, we have developed model systems that use plants and nematodes as …

Genomic responses in mouse models poorly mimic human inflammatory diseases

…, RW Davis, W Xiao, RG Tompkins… - Proceedings of the …, 2013 - National Acad Sciences
A cornerstone of modern biomedical research is the use of mouse models to explore basic
pathophysiological mechanisms, evaluate new therapeutic approaches, and make go or no-…

Isolation of rare circulating tumour cells in cancer patients by microchip technology

…, A Muzikansky, P Ryan, UJ Balis, RG Tompkins… - Nature, 2007 - nature.com
Viable tumour-derived epithelial cells (circulating tumour cells or CTCs) have been
identified in peripheral blood from cancer patients and are probably the origin of intractable …

A network-based analysis of systemic inflammation in humans

…, LL Moldawer, MN Mindrinos, RW Davis, RG Tompkins… - Nature, 2005 - nature.com
Oligonucleotide and complementary DNA microarrays are being used to subclassify histologically
similar tumours, monitor disease progress, and individualize treatment regimens 1 , 2 , …

Continuous inertial focusing, ordering, and separation of particles in microchannels

D Di Carlo, D Irimia, RG Tompkins… - Proceedings of the …, 2007 - National Acad Sciences
Under laminar flow conditions, when no external forces are applied, particles are generally
thought to follow fluid streamlines. Contrary to this perspective, we observe that flowing …

[HTML][HTML] Detection of Mutations in EGFR in Circulating Lung-Cancer Cells

…, D Irimia, J Settleman, RG Tompkins… - … England Journal of …, 2008 - Mass Medical Soc
Background The use of tyrosine kinase inhibitors to target the epidermal growth factor
receptor gene (EGFR) in patients with non–small-cell lung cancer is effective but limited by the …

A genomic storm in critically injured humans

…, RV Maier, RW Davis, RG Tompkins - Journal of Experimental …, 2011 - rupress.org
Human survival from injury requires an appropriate inflammatory and immune response. We
describe the circulating leukocyte transcriptome after severe trauma and burn injury, as well …

Common virulence factors for bacterial pathogenicity in plants and animals

…, EJ Stevens, SF Wolfort, J Shao, RG Tompkins… - Science, 1995 - science.org
… Because these males were mature at branding, and few males reappear every year, we
suggest that r = 10 is a reasonable value. Substituting and solving for Pi, we can identify two …