User profiles for T. Sayer

Tomi Sawyer

- Verified email at umass.edu - Cited by 15859

Taylor Sawyer, DO, MBA, MEd

- Verified email at uw.edu - Cited by 4708

Timothy Alexander Sayer

- Verified email at unimelb.edu.au - Cited by 631

[HTML][HTML] Functional brain plasticity associated with ACL injury: a scoping review of current evidence

T Neto, T Sayer, D Theisen, A Mierau - Neural plasticity, 2019 - hindawi.com
Anterior cruciate ligament (ACL) injury is a common problem with consequences ranging
from chronic joint instability to early development of osteoarthritis. Recent studies suggest that …

More than one way to debrief: a critical review of healthcare simulation debriefing methods

T Sawyer, W Eppich, M Brett-Fleegler… - Simulation in …, 2016 - journals.lww.com
Statement Debriefing is a critical component in the process of learning through healthcare
simulation. This critical review examines the timing, facilitation, conversational structures, and …

PCBs: structure–function relationships and mechanism of action

S Safe, S Bandiera, T Sawyer… - Environmental …, 1985 - ehp.niehs.nih.gov
Numerous reports have illustrated the versatility of polychlorinated biphenyls (PCBs) and
related halogenated aromatics as inducers of drug-metabolizing enzymes and the activity of …

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy

SM Gehrig, C van der Poel, TA Sayer, JD Schertzer… - Nature, 2012 - nature.com
… and plantaris) and diaphragm muscles were homogenized and subjected to sucrose gradient
differential centrifugation using a Thermo Scientific Sorvall WX100 ultracentrifuge with a T-…

[HTML][HTML] Social norms and risk perception: Predictors of distracted driving behavior among novice adolescent drivers

…, JS Zakrajsek, JT Shope, TB Sayer - Journal of Adolescent …, 2014 - Elsevier
Purpose Adolescent drivers are at elevated crash risk due to distracted driving behavior (DDB).
Understanding parental and peer influences on adolescent DDB may aid future efforts to …

[HTML][HTML] Reliability and measurement error of the Osteoarthritis Research Society International (OARSI) recommended performance-based tests of physical function in …

…, RS Hinman, M Hall, CJ Marshall, T Sayer… - Osteoarthritis and …, 2017 - Elsevier
Objective To estimate the reliability and measurement error of performance-based tests of
physical function recommended by the Osteoarthritis Research Society International (OARSI) …

[PDF][PDF] AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance

…, D Zhou, J Snodgrass, L Commodore, TK Sawyer… - Cancer cell, 2009 - cell.com
Inhibition of BCR-ABL by imatinib induces durable responses in many patients with chronic
myeloid leukemia (CML), but resistance attributable to kinase domain mutations can lead to …

Building insightful, memory-enriched models to capture long-time biochemical processes from short-time simulations

AJ Dominic III, T Sayer, S Cao… - Proceedings of the …, 2023 - National Acad Sciences
… We begin by considering some time t that is strictly greater than τ R and rewriting C ( t )
as … r + ℓ , we compute the time average of U on the time interval [t r , t r + ℓ ] using …

Stapled α− helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy

…, H Nash, LT Vassilev, TK Sawyer - Proceedings of the …, 2013 - National Acad Sciences
Stapled α−helical peptides have emerged as a promising new modality for a wide range of
therapeutic targets. Here, we report a potent and selective dual inhibitor of MDM2 and MDMX…

4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity.

TK Sawyer, PJ Sanfilippo, VJ Hruby… - Proceedings of the …, 1980 - National Acad Sciences
… a-MSH is more potent than a-MSH on both amphibian melanophores (2, 6) and on stimulating
melanoma adenylate cyclase (6, 13), and it isalso resistant to inactivation by chloramine-T