[HTML][HTML] Functional brain plasticity associated with ACL injury: a scoping review of current evidence
Anterior cruciate ligament (ACL) injury is a common problem with consequences ranging
from chronic joint instability to early development of osteoarthritis. Recent studies suggest that …
from chronic joint instability to early development of osteoarthritis. Recent studies suggest that …
More than one way to debrief: a critical review of healthcare simulation debriefing methods
Statement Debriefing is a critical component in the process of learning through healthcare
simulation. This critical review examines the timing, facilitation, conversational structures, and …
simulation. This critical review examines the timing, facilitation, conversational structures, and …
PCBs: structure–function relationships and mechanism of action
S Safe, S Bandiera, T Sawyer… - Environmental …, 1985 - ehp.niehs.nih.gov
Numerous reports have illustrated the versatility of polychlorinated biphenyls (PCBs) and
related halogenated aromatics as inducers of drug-metabolizing enzymes and the activity of …
related halogenated aromatics as inducers of drug-metabolizing enzymes and the activity of …
Hsp72 preserves muscle function and slows progression of severe muscular dystrophy
SM Gehrig, C van der Poel, TA Sayer, JD Schertzer… - Nature, 2012 - nature.com
… and plantaris) and diaphragm muscles were homogenized and subjected to sucrose gradient
differential centrifugation using a Thermo Scientific Sorvall WX100 ultracentrifuge with a T-…
differential centrifugation using a Thermo Scientific Sorvall WX100 ultracentrifuge with a T-…
[HTML][HTML] Social norms and risk perception: Predictors of distracted driving behavior among novice adolescent drivers
…, JS Zakrajsek, JT Shope, TB Sayer - Journal of Adolescent …, 2014 - Elsevier
Purpose Adolescent drivers are at elevated crash risk due to distracted driving behavior (DDB).
Understanding parental and peer influences on adolescent DDB may aid future efforts to …
Understanding parental and peer influences on adolescent DDB may aid future efforts to …
[HTML][HTML] Reliability and measurement error of the Osteoarthritis Research Society International (OARSI) recommended performance-based tests of physical function in …
Objective To estimate the reliability and measurement error of performance-based tests of
physical function recommended by the Osteoarthritis Research Society International (OARSI) …
physical function recommended by the Osteoarthritis Research Society International (OARSI) …
[PDF][PDF] AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
…, D Zhou, J Snodgrass, L Commodore, TK Sawyer… - Cancer cell, 2009 - cell.com
Inhibition of BCR-ABL by imatinib induces durable responses in many patients with chronic
myeloid leukemia (CML), but resistance attributable to kinase domain mutations can lead to …
myeloid leukemia (CML), but resistance attributable to kinase domain mutations can lead to …
Building insightful, memory-enriched models to capture long-time biochemical processes from short-time simulations
… We begin by considering some time t that is strictly greater than τ R and rewriting C ( t )
as … r + ℓ , we compute the time average of U on the time interval [t r , t r + ℓ ] using …
as … r + ℓ , we compute the time average of U on the time interval [t r , t r + ℓ ] using …
Stapled α− helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy
…, H Nash, LT Vassilev, TK Sawyer - Proceedings of the …, 2013 - National Acad Sciences
Stapled α−helical peptides have emerged as a promising new modality for a wide range of
therapeutic targets. Here, we report a potent and selective dual inhibitor of MDM2 and MDMX…
therapeutic targets. Here, we report a potent and selective dual inhibitor of MDM2 and MDMX…
4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity.
TK Sawyer, PJ Sanfilippo, VJ Hruby… - Proceedings of the …, 1980 - National Acad Sciences
… a-MSH is more potent than a-MSH on both amphibian melanophores (2, 6) and on stimulating
melanoma adenylate cyclase (6, 13), and it isalso resistant to inactivation by chloramine-T …
melanoma adenylate cyclase (6, 13), and it isalso resistant to inactivation by chloramine-T …